Guidance "Intermediates. Practical recommendations for use of intermediates in strictly controlled conditions and for development of a technical dossier in the latest version of IUCLID for registration purposes.

This guidance highlights the requirements for the use of chemical substances which are to be registered according to REACH Regulation and which may be registered under a simplified procedure - the registration of intermediate but adverse exposure of which must be fully minimized and controlled.

The main condition is the use of the substance in the so-called strictly controlled conditions, about what certain evidence shall be provided in order to have the right to follow the simplified procedure.

Guidance provides definitions and examples of such use of substances, a standard evidence base and examples of registration dossiers for intermediates.